WebAbout. Our laboratory is involved in the development of novel methods of single-molecule manipulation and detection, such as optical tweezers … WebWe propose an optical tweezers setup based on an annular-shaped laser beam that is efficient to trap 2.8 μ m-diameter superparamagnetic particles. The optical trapping of …
Optical Tweezers SpringerLink
WebDec 1, 2024 · Singlemolecule tweezers can explore the stretching and supercoiling properties of nucleic acids, (un)folding transitions and energy landscapes of some special nucleic acid structures like G4 or... WebAmong the most popular single-molecule manipulation techniques are AFM, and optical and magnetic tweezers, which we discuss in more detail below. Atomic force microscopy ( AFM, figure 3 d ). AFM ( Binnig et al. 1986) is part of the family of scanning probe microscopies, the first of which was scanning tunnelling microscopy ( Binnig & Rohrer 1982 ). soloam choir
Optical tweezers in single-molecule biophysics - Nature
WebOct 21, 2024 · Hermann Gaub is a co-founder of single-molecule biophysics, in particular through a series of pioneering work in which he established the manipulation and force spectroscopy of individual biomolecules using specially developed force microscopes. Many lecturers also highlighted the catalytic effect of the Center for NanoScience (CeNS), which … WebNov 29, 2024 · Once optical tweezers could manipulate single molecules while making dynamic force and length measurements, attention soon turned to DNA. A polymer that … WebSingle Molecular BioPhysics: Decapitating the beast of Averages. The Single-Molecule Biophysics team is headed by Prof Mark Leake, Anniversary Chair of Biological Physics and Coordinator of the Physics of Life Group. Prof Leake is a physicist by training but now address challenging biophysical and biochemical questions in a range of biological ... small bath vanity with sink