WebApr 6, 2024 · On 30 March, Roche published a press release stating that the Phase III pivotal SKYSCRAPER-02 trial of its investigational immunotherapy tiragolumab, in combination with Roche’s FDA-approved programmed cell death protein (PD)-1 inhibitor, Tecentriq (atezolizumab) and carboplatin and etoposide chemotherapy, in 490 patients with … WebMar 29, 2024 · The Phase III SKYSCRAPER-01 trial is currently ongoing to confirm the CITYSCAPE results. Since 2024, Genentech has initiated five Phase III trials, including …
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WebThis trial is registered with ClinicalTrials.gov, NCT03563716, and is ongoing. Findings: At data cutoff for the primary analysis (June 30, 2024), 135 of 275 patients assessed for eligibility were randomly assigned to receive tiragolumab plus atezolizumab (67 [50%]) or placebo plus atezolizumab (68 [50%]). WebMay 11, 2024 · The trial enrolled 534 patients who were randomized 1:1 to receive either tiragolumab, an anti-T cell immunoreceptor with Ig and ITIM domain (TIGIT) immunotherapy agent, plus atezolizumab or placebo plus atezolizumab until disease progression, loss of clinical benefit, or unacceptable toxicity. scoping method ansys
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WebClinical Trial Registration Number. NCT04256421. Citation. J Clin Oncol 40, 2024 (suppl 17; abstr LBA8507) DOI. 10.1200/JCO.2024.40.17_suppl.LBA8507. Abstract # LBA8507. Authors. ... SKYSCRAPER-02 (NCT04256421) evaluates whether the antitumor effect and survival benefits of the combination of atezo + CE could be enhanced by adding tira in pts ... WebJun 8, 2024 · The combination was well tolerated, and no new safety signals were identified. The study will continue to planned final OS analysis. Clinical trial information: … WebMar 1, 2024 · This is an international phase 2 trial. The team need 160 women worldwide to take part with 12 women from the UK. It is a randomised trial. You go into 1 of 2 treatment … scoping notice ct